TBX21 wt Allele

Preferred Label : TBX21 wt Allele;

NCIt synonyms : TBLYM; T-PET; T-bet; T-Box 21 wt Allele; TBET;

NCIt definition : Human TBX21 wild-type allele is located in the vicinity of 17q21.32 and is approximately 13 kb in length. This allele, which encodes T-box transcription factor TBX21 protein, plays a role in the transcriptional regulation of interferon-gamma. Genetic variation is associated with susceptibility to asthma with nasal polyps and aspirin intolerance.;

GenBank Accession Number : AF093098;

Details

Origin ID

C104249;

UMLS CUI

C3540638;

OMIM relation
- T-box transcription factor 21 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q21.32 [NCIt concept]
gene_is_element_in_pathway
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL27-Mediated Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cellular Migration Process [NCIt concept]
- DNA Binding [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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