NCIt definition : Human ENO1 wild-type allele is located in the vicinity of 1p36.2 and is approximately
18 kb in length. This allele, which encodes alpha-enolase protein, plays a role in
glycolysis and tumor suppression, and acts as a structural lens protein.;
NCIt note : An alternatively spliced product of this gene results in a shorter isoform that binds
to the c-myc promoter and functions as a tumor suppressor.;