Cytotoxic and Regulatory T-Cell Molecule

Preferred Label : Cytotoxic and Regulatory T-Cell Molecule;

NCIt synonyms : CD355 Antigen; Class I MHC Restricted T Cell Associated Molecule; Class-I MHC-Restricted T-Cell-Associated Molecule; CRTAM; Cytotoxic and Regulatory T Cell Molecule;

NCIt definition : Cytotoxic and regulatory T-cell molecule (393 aa, 47 kDa) is encoded by the human CRTAM gene. This protein is involved in promoting natural killer (NK) cell cytotoxicity and may promote interferon-gamma (IFN-gamma) secretion by CD8 cells.;

NCIt note : Cytotoxic and regulatory T-cell molecule is expressed as 2 isoforms as a result of alternative splicing. (UniProt);

Details

Origin ID

C104174;

UMLS CUI

C3539576;

Automatic exact mappings (from CISMeF team)
- Cytotoxic and regulatory t-cell molecule [OMIM gene]
- class-I restricted T cell-associated molecule [MeSH Supplementary Concept]
- cytotoxic and regulatory T cell molecule [HGNC gene]
OMIM relation
- Cytotoxic and regulatory t-cell molecule [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CRTAM Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients