Putative Inactive Neutral Ceramidase B

Preferred Label : Putative Inactive Neutral Ceramidase B;

NCIt synonyms : ASAH2B; ASAH2-Like Protein; Putative Inactive Non-Lysosomal Ceramidase B; Putative Inactive N-Acylsphingosine Amidohydrolase 2B;

NCIt definition : Putative inactive neutral ceramidase B (165 aa, 19 kDa) is encoded by the human ASAH2B gene. This protein may play a role in ceramide hydrolysis.;

NCIt note : Expression of putative inactive neutral ceramidase B decreases with age and in patients with late-onset Alzheimer disease. (UniProt); Putative inactive neutral ceramidase B has no predicted transmembrane domain, and lacks the active site, suggesting that it may be inactive. (UniProt);

Details

Origin ID

C103907;

UMLS CUI

C3537384;

OMIM relation
- N-acylsphingosine amidohydrolase 2b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ASAH2B Gene [NCIt concept]
- Regulatory Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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