NCIt related terms : Acetamide, N-[(methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]- (9CI);
NCIt definition : An agent derived from acetohydroxamic acid with potential antineoplastic activity.
Caracemide inhibits ribonuclease reductase, resulting in decreased DNA synthesis and
tumor growth; it also inhibits acetylcholinesterase. In vivo, caracemide contributes
to the formation of the neurotoxin methyl isocyanate; this effect, along with the
agent's acetylcholinesterase activity, may be responsible for the severe central nervous
system toxicity observed in clinical trials. (NCI04);
UNII : H74F6J185A;
InChIKey : JURAJLFHWXNPHG-UHFFFAOYSA-N;
CAS number : 81424-67-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 81424-67-1
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