" /> Caracemide - CISMeF





Preferred Label : Caracemide;

NCIt synonyms : N-Acetyl-N-(methylcarbamoyloxy)-N'-methylurea; Acetamide, N-[(Methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]-(9CI);

NCIt related terms : Acetamide, N-[(methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]- (9CI);

NCIt definition : An agent derived from acetohydroxamic acid with potential antineoplastic activity. Caracemide inhibits ribonuclease reductase, resulting in decreased DNA synthesis and tumor growth; it also inhibits acetylcholinesterase. In vivo, caracemide contributes to the formation of the neurotoxin methyl isocyanate; this effect, along with the agent's acetylcholinesterase activity, may be responsible for the severe central nervous system toxicity observed in clinical trials. (NCI04);

UNII : H74F6J185A;

InChIKey : JURAJLFHWXNPHG-UHFFFAOYSA-N;

CAS number : 81424-67-1;

Chemical formula : C6H11N3O4;

NSC code : 253272;

Codes from synonyms : NSC0253272;

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02/06/2025


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