Preferred Label : Fluorine F 18 4-L-fluoroglutamine (2S,4R);
NCIt synonyms : 18F Fluoroglutamine; [18F] 4-L-fluoroglutamine (2S,4R);
NCIt definition : A radioconjugate and glutamine analog consisting of the fluorine F 18 labeled 2S,
4R stereoisomer of 4-fluoroglutamine with potential use as a metabolic tracer for
tumor imaging. Upon intravenous administration, fluorine F 18 4-L-fluoroglutamine
(2S,4R) is preferentially taken up by cancer cells, possibly driven by c-Myc upregulation.
Upon positron emission tomography (PET), cancer cells can be imaged. Tumor cells use
the amino acid glutamine for nutritional purposes necessary for energy production
and growth; as tumor cells proliferate more rapidly than normal healthy cells, glutamine
uptake is higher in certain cancer cells.;
NCI Metathesaurus CUI : CL437435;
Origin ID : C103196;
UMLS CUI : C3641124;
Semantic type(s)
- concept_is_in_subset
