Preferred Label : Src/Abl Kinase Inhibitor AZD0424;
NCIt related terms : AZD-0424;
NCIt definition : An orally bioavailable small molecule tyrosine kinase inhibitor that targets both
Abl and Src kinases with potential antineoplastic activity. Upon oral administration,
AZD0424 selectively inhibits both Src and Abl kinase activity which may result in
the inhibition of tumor growth in susceptible tumor cells. Src and Abl kinases are
upregulated in certain tumor cells and play important roles in tumor cell proliferation
and metastasis.;
UNII : 642PS51324;
CAS number : 692054-06-1;
Molecule name : AZD0424;
NCI Metathesaurus CUI : CL437215;
Origin ID : C102976;
UMLS CUI : C4519307;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
