PIK3C2G wt Allele

Preferred Label : PIK3C2G wt Allele;

NCIt synonyms : PI3K-C2GAMMA; Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Gamma wt Allele; Phosphoinositide-3-Kinase, Class 2, Gamma Polypeptide Gene; PI3K-C2-Gamma; Phosphatidylinositol 3-Kinase, Class 2, Gamma Gene; Phosphatidylinositol-4-Phosphate 3-Kinase, Catalytic Subunit Type 2 Gamma Gene;

NCIt definition : Human PIK3C2G wild-type allele is located in the vicinity of 12p12 and is approximately 401 kb in length. This allele, which encodes phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma protein, plays a role in both the phosphorylation of phospholipids and the modulation of second messenger signaling.;

NCIt note : Overexpression of the PIK3C2G gene may be associated with the SHH-dependent subgroup of medulloblastoma.. (Nature. 2012; 488:49-56.);

GenBank Accession Number : AJ000008;

Details

Origin ID

C102946;

UMLS CUI

C3541408;

OMIM relation
- Phosphatidylinositol 3-kinase, class 2, gamma [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12p12 [NCIt concept]
gene_is_element_in_pathway
- CCR3 Signaling Pathway [NCIt concept]
- CXCR4 Signaling Pathway [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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