PIK3C2B wt Allele

Preferred Label : PIK3C2B wt Allele;

NCIt synonyms : C2-PI3K; RP11-739N20.5; PI3K-C2beta; Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Beta wt Allele; PI3KC2B; Phosphatidylinositol-4-Phosphate 3-Kinase, Catalytic Subunit Type 2 Beta Gene;

NCIt definition : Human PIK3C2B wild-type allele is located in the vicinity of 1q32 and is approximately 72 kb in length. This allele, which encodes phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta protein, plays a role in the regulation of phosphoinositol signaling.;

NCIt note : Overexpression of the PIK3C2B gene may be associated with the SHH-dependent subgroup of medulloblastoma. (Nature. 2012; 488:49-56.);

GenBank Accession Number : Y11312;

Details

Origin ID

C102943;

UMLS CUI

C3539773;

OMIM relation
- Phosphatidylinositol 3-kinase, class 2, beta [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1q32 [NCIt concept]
gene_is_element_in_pathway
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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