EOMES wt Allele

Preferred Label : EOMES wt Allele;

NCIt synonyms : T-Box, Brain, 2 Gene; TBR2; Eomesodermin wt Allele; Eomesodermin (Xenopus laevis) Homolog Gene; Eomesodermin, Xenopus, Homolog of Gene;

NCIt definition : Human EOMES wild-type allele is located 3p24.1 and is approximately 7 kb in length. This allele, which encodes eomesodermin homolog protein, is involved in both embryonic development and the regulation of gene transcription.;

NCIt note : Aberrant expression of the EOMES gene may be associated with medulloblastoma. (Nature. 2012; 488:100-105.);

GenBank Accession Number : BC025363;

Details

Origin ID

C102928;

UMLS CUI

C3541324;

OMIM relation
- Eomesodermin [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Embryogenesis [NCIt concept]
- Nervous System Development [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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