Preferred Label : Boanmycin Hydrochloride;
NCIt synonyms : BAM HCl;
NCIt related terms : Bleomycin A6 Hydrochloride;
NCIt definition : The hydrochloride salt form of boanmycin (aka bleomycin A6), a component of the antibiotic
bleomycin produced by Streptomyces species, with potential antineoplastic activity.
Upon administration, boanmycin forms complexes with iron that reduce molecular oxygen
to superoxide and hydroxyl radicals. This causes single- and double-stranded DNA breaks
which eventually leads to cell death. Compared to bleomycin, boanmycin appears to
have a more favorable toxicity profile.;
UNII : K4QGS58U92;
NCI Metathesaurus CUI : CL437181;
Codes from synonyms : NSC0125066;
Origin ID : C102878;
UMLS CUI : C3640990;
Semantic type(s)
- concept_is_in_subset
