Preferred Label : HPV-16 E6 Peptides Vaccine/Candida albicans Extract;
NCIt synonyms : HPV-16 E6 Peptides Vaccine/Candin;
NCIt definition : A human papillomavirus (HPV) type 16 vaccine containing four E6 peptides in combination
with an extract of Candida albicans, with potential immunomodulating and antineoplastic
activities. Upon administration of HPV-16 E6 peptides vaccine/Candida albicans extract,
the four HPV-16 E6 peptides and the Candida albicans may activate the immune system
to mount a cytotoxic T-lymphocyte (CTL) response against cells expressing the E6 oncoprotein,
resulting in tumor cell lysis. The HPV 16 transforming protein E6 is expressed in
precancerous and malignant cervical lesions, and HPV may be a cause of some head and
neck squamous cell carcinomas (HNSCCs). Candida albicans allergenic extract may be
used as a recall antigen to stimulate the immune system against HPV.;
Drug name : PepCan;
NCI Metathesaurus CUI : CL437177;
Origin ID : C102874;
UMLS CUI : C3640984;
Semantic type(s)
- concept_is_in_subset
- has_target
