Preferred Label : Ulimorelin Hydrochloride;
NCIt synonyms : (2R,5S,8R,11R)-5-Cyclopropyl-11-((4-fluorophenyl)methyl)-2,7,8-trimethyl-2,3,4,5,7,8,10,11,13,14,15,16-dodecahydro-6H-1,4,7,10,13-
benzoxatetraazacyclooctadecine-6,9,12-trione Hydrochloride Monohydrate;
NCIt definition : The hydrochloride salt form of ulimorelin, a macrocyclic ghrelin peptidomimetic, with
potential gastrointestinal (GI) prokinetic activity. Upon intravenous administration,
ulimorelin binds to the ghrelin receptor in the GI tract and may stimulate GI motility.
Ghrelin is a natural ligand for growth hormone secretagogue receptors and is normally
localized in the proximal GI tract. The ghrelin receptor signaling pathway mediates
multiple GI functions, including motility and gastric emptying.;
UNII : 662MCS79XH;
InChIKey : ZWIXEQBDJMFCMN-DHHNQDMHSA-N;
CAS number : 951326-02-6;
Molecule name : TZP-101;
Origin ID : C102755;
UMLS CUI : C4682388;
Semantic type(s)
- concept_is_in_subset
