Preferred Label : Bruceantin;
NCIt synonyms : 2H-3, 11c-(Epoxymethano)phenanthro[10,1-bc]pyran, Picras-3-en-21-oic Acid Derivative; [11Beta,12alpha,15beta(E)]-15-[(3,4-dimethyl-1-oxo-2-pentenyl)oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxopicras-3-en-21-oic
Acid Methyl Ester; Picras-3-en-21-oic Acid, 15-[(3,4-dimethyl-1-oxo-2-pentenyl)oxy]-13,20-epoxy-3,11,
12-trihydroxy-2,16-dioxo-, Methyl Ester, (11beta,12alpha,15beta(E));
NCIt related terms : Picras-3-en-21-oic acid, 15-[(3, 4-dimethyl-1-oxo-2-pentenyl)oxy]-13,20-epoxy-3,11,12-trihydroxy-2,
16-dioxo-, methyl ester [11.beta.,12.alpha.,15.beta.(E)]-; Picras-3-en-21-oic acid, 15-[(3, 4-dimethyl-1-oxo-2-pentenyl)oxy]-13,20-epoxy-3,11,12-trihydroxy-2,
16-dioxo-, methyl ester, [11.beta.,12.alpha.,15.beta.(E)]-;
NCIt definition : A triterpene quassinoid antineoplastic antibiotic isolated from the plant Brucea antidysenterica.
Bruceantin inhibits the peptidyl transferase elongation reaction, resulting in decreased
protein and DNA synthesis. Bruceantin also has antiamoebic and antimalarial activity.
(NCI04);
UNII : S3NW88DI4T;
CAS number : 41451-75-6;
NSC code : 165563;
Codes from synonyms : 50082; NSC0165563;
Origin ID : C1025;
UMLS CUI : C0054160;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
