Lipopolysaccharide

Preferred Label : Lipopolysaccharide;

NCIt synonyms : LPS;

NCIt definition : An endotoxin and biologically active component of the Gram-negative bacterial cell wall that is a Toll-like receptor 4 (TLR4) agonist with potential immunostimulatory activity. Upon internalization, lipopolysaccharide (LPS) activates TLR4 which in turn activates the NFkappaB pathway, in addition to mitogen-activated protein kinases signaling pathways. This leads to the release of proinflammatory cytokines and stimulates an innate immune response against vaccine antigens.;

ChEBI ID : CHEBI:16412;

Details

Origin ID

C101788;

UMLS CUI

C0023810;

Automatic exact mappings (from CISMeF team)
- Lipopolysaccharide [FMA entity]
- Lipopolysaccharide (substance) [SNOMED CT concept]
- Lipoprotein (a) (substance) [SNOMED CT concept]
- Lipoprotein a [LOINC component]
- Van der woude syndrome 1 [OMIM Phenotype]
- lipopolysaccharide A [MeSH concept]
- lipopolysaccharide A [MeSH Supplementary Concept]
- lipopolysaccharide, nos [SNOMED Notion]
- lipopolysaccharides [MeSH Descriptor]
- lipopolysaccharides [MeSH concept]
- lipopolysaccharides [IUPAC Term]
- re lipopolysaccharide [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Lipopolysaccharide [FMA entity]
- Lipopolysaccharide (substance) [SNOMED CT concept]
- lipopolysaccharide, nos [SNOMED Notion]
- lipopolysaccharides [MeSH Descriptor]
- lipopolysaccharides [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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