Preferred Label : Iobenguane I-124;
NCIt synonyms : Iodine I 124 Metaiodobenzylguanidine; Iodine I 124 Iobenguane; 124I-metaiodobenzylguanidine; 124I-MIBG;
NCIt definition : A radioconjugate composed of the positron-emitting radioisotope iodine I 124 labeled
to iobenguane, the synthetic aralkylguanidine analogue of the neurotransmitter norepinephrine
(NE), with potential diagnostic imaging applications upon positron emitting tomography
(PET) or computed tomography (CT). Upon administration, iobenguane I-124 is taken
up and accumulates in the granules of adrenal medullary chromaffin cells and in the
pre-synaptic granules of adrenergic neurons in a manner almost identical with that
of NE. In turn, tumor cells can be imaged upon PET or CT.;
UNII : K2349O62GE;
InChIKey : PDWUPXJEEYOOTR-JMWSGNKWSA-N;
CAS number : 119159-02-3;
NCI Metathesaurus CUI : CL435900;
Origin ID : C101776;
UMLS CUI : C3640210;
Semantic type(s)
- concept_is_in_subset
- has_target
