TFF3 wt Allele

Preferred Label : TFF3 wt Allele;

NCIt synonyms : HITF; TFI; ITF; Trefoil Factor 3 (Intestinal) wt Allele; P1B;

NCIt definition : Human TFF3 wild-type allele is located in the vicinity of 21q22.3 and is approximately 4 kb in length. This allele, which encodes trefoil factor 3 protein, plays a role in cell motility and both repair and maintenance of the intestinal mucosa.;

NCIt note : The TFF3 gene is expressed in both normal breast epithelium and in diseased breast tissue. (Am J Pathol. 2012; 180:904-916.);

GenBank Accession Number : AF432265;

Details

Origin ID

C101770;

UMLS CUI

C3538698;

OMIM relation
- Trefoil factor 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 21q22.3 [NCIt concept]
gene_is_element_in_pathway
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
- Mucosal Healing Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Motility [NCIt concept]
- Digestion [NCIt concept]

Keyword's position in hierarchy(ies) :

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