NCIt definition : Human ATF5 wild-type allele is located in the vicinity of 19q13.3 and is approximately
5 kb in length. This allele, which encodes cyclic AMP-dependent transcription factor
ATF-5 protein, plays a role in the modulation of transcription.;
NCIt note : Polymorphism of the ATF5 gene can affect the efficacy of treatment for patients with
childhood acute lymphoblastic leukemia. (Blood. 2011; 118: 5883-5890.);