MX2 wt Allele - CISMeF

Preferred Label : MX2 wt Allele;

NCIt synonyms : Myxovirus (Influenza Virus) Resistance 2 (Mouse) wt Allele; MXB;

NCIt definition : Human MX2 wild-type allele is located in the vicinity of 21q22.3 and is approximately 46 kb in length. This allele, which encodes interferon-induced GTP-binding protein Mx2, is involved in both binding and hydrolysis of GTP.;

NCIt note : A SNP located in an intron of the MX2 gene may be associated with susceptibility to melanoma. (Nature Genetics. 2011; 43:1108-1113.);

GenBank Accession Number : NM_002463;

Details

Origin ID

C101553;

UMLS CUI

C3540578;

OMIM relation
- Mx dynamin-like gtpase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 21q22.3 [NCIt concept]
gene_plays_role_in_process
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Immune System Process [NCIt concept]
- Interferon Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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