NCIt definition : The hydrochloride salt of a dihydropyridine derivative with diuretic and antihypertensive
activity. Cicletanine exerts thiazide-like diuretic activity. In addition, this agent
inhibits protein kinase C (PKC) and is able to reverse vasoconstriction through the
inhibition of PKC-mediated inhibition of Na/K-ATPase phosphorylation.;