FLT3/KIT Kinase Inhibitor AKN-028

Preferred Label : FLT3/KIT Kinase Inhibitor AKN-028;

NCIt related terms : AKN-028;

NCIt definition : An orally bioavailable protein tyrosine kinase inhibitor for FMS-related tyrosine kinase 3 (FLT3; STK1) and stem cell factor receptor (SCFR; KIT), with potential antineoplastic activity. FLT3/KIT kinase inhibitor AKN-028 binds to and inhibits both the wild-type and mutated forms of FLT3 and SCFR. This may result in an inhibition of tumor cell proliferation in cancer cell types that overexpress these receptor tyrosine kinases.;

UNII : Y66IS3CS0R;

CAS number : 1175017-90-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1175017-90-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : AKN-028; BVT-II;

Details

Origin ID

C101520;

UMLS CUI

C3852612;

Currated CISMeF NLP mapping
- AKN -028 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- AKN -028 [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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