" /> GRN wt Allele - CISMeF





Preferred Label : GRN wt Allele;

NCIt synonyms : GP88; PCDGF; CLN11; GEP; Granulin Precursor wt Allele; PGRN; PEPI; Granulin Gene; Glycoprotein, 88-kD Gene; Granulin-Epithelin Gene;

NCIt definition : Human GRN wild-type allele is located in the vicinity of 17q21.32 and is approximately 8 kb in length. This allele, which encodes progranulin protein, plays a role in wound healing, lysosome acidification and the modulation of inflammation. Mutation of the gene is associated with primary progressive aphasia, neuronal ceroid lipofuscinosis type 11 and ubiquitin-positive frontotemporal dementia.;

GenBank Accession Number : M75161;

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31/07/2025


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