NCIt synonyms : Benzoporphyrin Derivative Monoacid Ring A; BPD-MA;
NCIt definition : A synthetic light-activated agent with photodynamic activity. Upon systemic administration,
verteporfin accumulates in neovessels in the eye and, once stimulated by nonthermal
red light in the presence of oxygen, produces highly reactive short-lived singlet
oxygen and other reactive oxygen radicals, resulting in local damage to neovascular
endothelium and blood vessel occlusion. (NCI04);