Integrin AlphaM/Beta2

Preferred Label : Integrin AlphaM/Beta2;

NCIt synonyms : CD11b/CD18; Mac-1; CR3; Macrophage-1 Antigen; Complement Receptor 3; Integrin Alpha-M/Beta-2;

NCIt definition : Integrin alpha-M/beta2 is a protein complex comprised of a heterodimer of integrin alpha M and integrin beta 2. This complex is involved in anti-bacterial defense and complement internalization.;

NCI Metathesaurus CUI : CL435599;

Details

Origin ID

C101289;

UMLS CUI

C0079785;

Automatic exact mappings (from CISMeF team)
- Lymphocyte antigen CD11b (substance) [SNOMED CT concept]
- Lymphocyte antigen CD18 (substance) [SNOMED CT concept]
- carbidopa, levodopa drug combination [MeSH Supplementary Concept]
- integrin alphaXbeta2 [MeSH Descriptor]
- integrin subunit alpha M [ORDO Gene]
- integrin subunit beta 2 [ORDO Gene]
Currated CISMeF NLP mapping
- Complement receptor 3 [LOINC component]
- Macrophage-1 antigen [MeSH concept]
- complement receptor 3 [SNOMED Notion]
- macrophage-1 antigen [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Complement receptor 3 [LOINC component]
- Macrophage-1 antigen [MeSH concept]
- complement receptor 3 [SNOMED Notion]
- mac-1 leukocyte adhesive protein [SNOMED Notion]
- macrophage-1 antigen [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_expressed_in_tissue
- Leukocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Adhesion Molecule [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Ligand Binding [NCIt concept]
has_gene_product_element
- Integrin Alpha-M [NCIt concept]
- Integrin Beta-2 [NCIt concept]
related_to_genetic_biomarker
- ITGAM Gene [NCIt concept]
- ITGB2 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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