Beauvericin - CISMeF

Preferred Label : Beauvericin;

NCIt definition : A cyclic hexadepsipeptide antibiotic and mycotoxin isolated from the fungus Beauveria bassiana and various Fusarium fungal species. As a potassium-specific ionophore, beauvericin A increases intracellular calcium concentrations and triggers DNA fragmentation and apoptosis through a calcium dependent caspase 3-sensitive pathway. This agent has been studied as a potential antineoplastic agent. (NCI04);

UNII : 26S048LS2R;

CAS number : 26048-05-5;

ChEBI ID : CHEBI:3000;

Details

Origin ID

C1011;

UMLS CUI

C0053065;

Currated CISMeF NLP mapping
- beauvericin [MeSH concept]
- beauvericin [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
UMLS correspondences (same concept)
- beauvericin [MeSH concept]
- beauvericin [MeSH Supplementary Concept]
chemical_or_drug_has_physiologic_effect
- Immunosuppressive Effect [NCIt concept]
- Ion Transport Process [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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