NPM1/RARA Short Fusion Gene

Preferred Label : NPM1/RARA Short Fusion Gene;

NCIt synonyms : NPM1-RARA Short Fusion Gene; NPM-RAR Short Form; NPM1::RARA Short Fusion Gene;

NCIt definition : A fusion gene ( 1.9 kb) that results from a chromosomal translocation t(5;17)(q35;q21) which fuses the first 442 nucleotides of the NPM1 gene to exon 3 of the RARA gene. This rearrangement is rare and is associated with acute myeloid leukemia.;

GenBank Accession Number : U41743;

PubMed : 8562957;

Détails

Origin ID

C101063;

UMLS CUI

C3639971;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_encodes_gene_product
- NPM1/RARA Short Fusion Protein [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Promyelocytic Leukemia with t(5;17)(q35;q21); NPM1-RARA [NCIt concept]
gene_mapped_to_disease
- Acute Promyelocytic Leukemia with t(5;17)(q35;q21); NPM1-RARA [NCIt concept]
related_to_genetic_biomarker
- NPM1 Gene [NCIt concept]
- RARA Gene [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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