MLL/ELL Fusion Gene

Preferred Label : MLL/ELL Fusion Gene;

NCIt synonyms : MLL-ELL Fusion Gene; KMT2A-ELL Fusion Gene; KMT2A/ELL Fusion Gene; KMT2A::ELL Fusion Gene; MLL::ELL Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13.1) which fuses the first 7 exons of the MLL gene to most of the coding sequence of the ELL gene. This rearrangement is associated with treatment-related acute myeloid leukemia.;

Details

Origin ID

C101057;

UMLS CUI

C3639966;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- MLL/ELL Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- KMT2A-ELL Fusion Protein Expression [NCIt concept]
gene_mapped_to_disease
- Acute Myeloid Leukemia with t(11;19)(q23.3;p13.1); KMT2A-ELL [NCIt concept]
related_to_genetic_biomarker
- ELL Gene [NCIt concept]
- KMT2A Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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