Preferred Label : Retinopathy of Prematurity with Plus Disease;
NCIt definition : A stage of retinopathy of prematurity characterized by the presence of the following
in at least two quadrants around the optic nerve: dilation and tortuosity of major
retinal vasculature as a result of increased blood flow.;
Alternative definition : NICHD: A vasoproliferative condition of very immature newborn infants that may be
characterized by neovascularization, scarring, retinal detachment, and eventually
blindness. Plus disease is characterized by at least two quadrants around the optic
nerve showing evidence of dilation and tortuosity of the major retinal vessels resulting
from increased blood flow or neovascularization of the iris or poor view of the retina
due to vitreous haze.;
Origin ID : C101036;
UMLS CUI : C3639958;
Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
