Preferred Label : Alzheimer's Disease Assessment Scale-Cognitive CDISC Version Functional Test;
NCIt related terms : ADAS-COG; ADC;
NCIt definition : The CDISC version of the Alzheimer's Disease Assessment Scale-Cognitive (CDISC ADAS-Cog)
containing 15 summary-level tests. This version is based on combining the total pool
of ADAS-Cog tests that were observed during a review of multiple case report forms
administered in clinical trials of Alzheimer's disease, as well as the CRF administered
in the Alzheimer's Disease Neuroimaging Initiative (ADNI) observational study. (Modified
from Mohs RC, Rosen WG, Davis KL. The Alzheimer's disease assessment scale: an instrument
for assessing treatment efficacy. Psychopharmacol Bull 1983;19(3):448-450. Rosen WG,
Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984;141(11):1356-1364.
Mohs RC, Knopman D, Petersen RC et al. Development of cognitive instruments for use
in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment
Scale that broaden its scope. The Alzheimer's Disease Cooperative Study. Alzheimer
Dis Assoc Disord 1997;11 Suppl 2:S13-S21. Wouters H, van Gool WA, Schmand B, Lindeboom
R. Revising the ADAS-cog for a more accurate assessment of cognitive impairment. Alzheimer
Dis Assoc Disord 2008;22(3):236-244.).;
Alternative definition : CDISC: The CDISC version of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog
CDISC Version) containing 15 summary-level tests. This version is based on combining
the total pool of ADAS-Cog tests that were observed during a review of multiple case
report forms administered in clinical trials of Alzheimer's disease, as well as the
CRF administered in the Alzheimer's Disease Neuroimaging Initiative (ADNI) observational
study. (Modified from Mohs RC, Rosen WG, Davis KL. The Alzheimer's disease assessment
scale: an instrument for assessing treatment efficacy. Psychopharmacol Bull 1983;19(3):448-450.
Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry
1984;141(11):1356-1364. Mohs RC, Knopman D, Petersen RC et al. Development of cognitive
instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's
Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative
Study. Alzheimer Dis Assoc Disord 1997;11 Suppl 2:S13-S21. Wouters H, van Gool WA,
Schmand B, Lindeboom R. Revising the ADAS-cog for a more accurate assessment of cognitive
impairment. Alzheimer Dis Assoc Disord 2008;22(3):236-244.).;
Origin ID : C100762;
UMLS CUI : C3539026;
Semantic type(s)
- concept_is_in_subset
