Glypican-3 - CISMeF

Preferred Label : Glypican-3;

NCIt synonyms : MXR7; GTR2-2; Glypican 3; Intestinal Protein OCI-5; Glypican Proteoglycan 3;

NCIt related terms : GPC3;

NCIt definition : Glypican-3 (580 aa, 66 kDa) is encoded by the human GPC3 gene. This protein is involved in the mediation of proteoglycan binding to the cell surface.;

NCIt note : Glypican-3 can be processed into a form that is soluble and secreted into the extracellular space.;

Details

Origin ID

C88175;

UMLS CUI

C1308086;

Currated CISMeF NLP mapping
- Glypican-3 [MeSH concept]
OMIM relation
- Glypican 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GPC3 protein, human [MeSH concept]
- GPC3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GCT Authorized Value Terminology [NCIt concept]
- GCT Immunohistochemistry Table [NCIt concept]
gene_encodes_gene_product
- GPC3 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Proteoglycan [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glypican 3 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
is_target
- Anti-GPC3-CAR Autologous T Lymphocytes [NCIt concept]
- Anti-GPC3/Anti-4-1BB Bispecific Antibody BGB-B2033 [NCIt concept]
- Anti-GPC3/Anti-CD3 Bispecific Antibody CM350 [NCIt concept]
- Anti-GPC3/TCR Nanobody SAR444200 [NCIt concept]
- Anti-Glypican 3-scFvGC33-CAR-expressing T Lymphocytes [NCIt concept]
- Anti-Glypican 3/CD3 Bispecific Antibody ERY974 [NCIt concept]
- Autologous Anti-GPC3 CAR T Cells BOXR1030 [NCIt concept]
- Autologous Anti-GPC3 CAR T-lymphocytes JWAT204 [NCIt concept]
- Autologous Anti-GPC3-CAR T-lymphocytes Ori-C101 [NCIt concept]
- Autologous Anti-glypican-3 CAR-IL-15-iC9-expressing T-lymphocytes [NCIt concept]
- Autologous IL-15/IL-21-armored Anti-glypican-3 CAR T-cells [NCIt concept]
- Autologous Interleukin-15-armored Anti-glypican-3 CAR-iC9-expressing T-lymphocytes [NCIt concept]
- Autologous dnTGF-BRII-armored Anti-GPC3 CAR T-cells AZD5851 [NCIt concept]
- Codrituzumab [NCIt concept]
- ECT204 Transgene-transduced Autologous T Cells ECT204 [NCIt concept]
- GPC3-targeted Plasmid DNA Vaccine NWRD06 [NCIt concept]
- IRDye800CW-labeled GPC3-targeted Agent [NCIt concept]

Keyword's position in hierarchy(ies) :

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