Preferred Label : HPV E1/E2 Interaction Inhibitor Gel AP611074;
NCIt synonyms : Protein/Protein Interaction Inhibitor AP611074; PPI inhibitor AP611074;
NCIt definition : A topical gel composed of a human papillomavirus (HPV) E1/E2 protein:protein interaction
(PPI) inhibitor with potential antiviral activity. Upon topical application of AP611074,
this agent prevents binding of the HPV viral proteins E1 to E2, thereby preventing
viral DNA replication and growth of HPV. This inhibits viral proliferation and may
prevent the formation of anogenital warts caused by HPV. The HPV proteins E1 and E2
are essential for HPV viral replication.;
Molecule name : AP611074;
NCI Metathesaurus CUI : CL433976;
Origin ID : C100100;
UMLS CUI : C3639092;
Semantic type(s)
- concept_is_in_subset
