Rintatolimod - CISMeF

Preferred Label : Rintatolimod;

NCIt synonyms : Poly(I).Poly(c12,U); Poly(Inosinic Acid) Poly(Cytidylic(12), Uridylic)Acid; Atvogen;

NCIt related terms : Ampligen;

NCIt definition : A synthetic derivative of inosinic acid with antiretroviral and immunomodulatory properties. Atvogen acts through a number of pathways to stimulate intracellular antiviral activity of the immune system: it stimulates interferon production; activates the oligoadenylate synthase-RNase L pathway; stimulates natural killer cell activity; and acts as a non-mitogenic stimulator of the immune system. This agent also inhibits replication of human immunodeficiency virus (HIV) in vitro. (NCI04);

UNII : 94325AJ25N;

CAS number : 38640-92-5;

Drug name : Ampligen;

Chemical formula : ((C9H11N2O8P)n(C9H12N3O7P)n)ran.(C10H11N4O7P)n;

NSC code : 616524;

Codes from synonyms : NSC0616524;

Details

Origin ID

C1001;

UMLS CUI

C1434913;

Automatic exact mappings (from CISMeF team)
- ampligen [MeSH concept]
Currated CISMeF NLP mapping
- poly(I).poly(c12,U) [MeSH Supplementary Concept]
- poly(I).poly(c12,U) [MeSH concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- poly(I).poly(c12,U) [MeSH concept]
- poly(I).poly(c12,U) [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Ampligen/Interleukin-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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