Conjunctival Melanocytic Intraepithelial Lesion

Preferred Label : Conjunctival Melanocytic Intraepithelial Lesion;

NCIt synonyms : Primary Acquired Melanosis with Atypia; Conjunctival Primary Acquired Melanosis with Atypia; Conjunctival Melanocytic Intraepithelial Neoplasia; C-MIL; PAM with Atypia; C-MIN;

NCIt definition : A spectrum of neoplastic changes that occur in the conjunctiva and range from melanocytic hyperplasia through degrees of atypia to melanoma in situ. The lesions are generally unilateral but often multifocal and appear as flat, irregular brown discolorations of the conjunctiva. They usually affect middle-aged and elderly Caucasians. (WHO 2018);

Neoplastic status : Undetermined;

Details

Origin ID

C100054;

UMLS CUI

C3263719;

Automatic exact mappings (from CISMeF team)
- Conjunctival primary acquired melanosis [MedDRA Preferred Term]
- Microscopic polyangiitis [ORDO Disease]
- Myc-binding protein 2 [OMIM gene]
- Peptidylglycine alpha-amidating monooxygenase [OMIM gene]
- Potassium-aggravated myotonia [ORDO Disease]
- Pralidoxime [ICD-11 Extension code]
- microscopic polyangiitis [MeSH Descriptor]
Disease may have findings
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- Melanocytic Dysplasia [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
Has associated anatomic sites
- Conjunctiva [NCIt concept]
- Eye [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Conjunctival primary acquired melanosis [MedDRA Preferred Term]
- Primary acquired melanocytic nevus of conjunctiva (disorder) [SNOMED CT concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Melanocyte [NCIt concept]
disease_has_finding
- Cytologic Atypia [NCIt concept]
- Non-Invasive Lesion [NCIt concept]
disease_has_normal_cell_origin
- Melanocyte [NCIt concept]
disease_has_normal_tissue_origin
- Conjunctival Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Conjunctiva [NCIt concept]

Keyword's position in hierarchy(ies) :

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