1-(4-(5'-chloro-3,5-dimethyl-2,4'-bipyridin-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one

Preferred Label : 1-(4-(5'-chloro-3,5-dimethyl-2,4'-bipyridin-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one;

MeSH note : a potent and selective Smoothened antagonist that penetrates the blood-brain barrier; structure in first source;

CISMeF synonym : PF-5274857;

Is substance : O;

Details

Origin ID

C573117;

UMLS CUI

C3493016;

MeSH term(s) associated for indexing
- 2,2'-Dipyridyl [MeSH Descriptor]
- piperazines [MeSH Descriptor]
Record concept(s)
- 1-(4-(5'-chloro-3,5-dimethyl-2,4'-bipyridin-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one [MeSH concept]
- PF-5274857 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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