pevonedistat - CISMeF

Preferred Label : pevonedistat;

MeSH note : a potent and selective inhibitor of NAE (NEDD8-activating enzyme);

CISMeF synonym : 4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl methyl sulphamidate; MLN4924; 4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl methyl sulfamidate;

MeSH synonym : ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate; ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulphamate;

MeSH hyponym : MLN-4924;

Is substance : O;

UNII : S3AZD8D215;

Details

Origin ID

C539933;

UMLS CUI

C2703093;

Automatic exact mappings (from CISMeF team)
- Pevonedistat [NCIt concept]
MeSH term(s) associated for indexing
- cyclopentanes [MeSH Descriptor]
- pyrimidines [MeSH Descriptor]
Pharmacological action(s)
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- 4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl methyl sulfamidate [MeSH concept]
- MLN4924 [MeSH concept]
- pevonedistat [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pevonedistat [NCIt concept]

Keyword's position in hierarchy(ies) :

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