darapladib - CISMeF

Preferred Label : darapladib;

MeSH note : a selective lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) inhibitor, on biomarkers of cardiovascular (CV) risk;

MeSH synonym : N-(2-(diethylamino)ethyl)-2-(2-((4-fluorobenzyl)sulfanyl)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopentapyrimidin-1-yl)-N-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)acetamide;

Is substance : O;

UNII : UI1U1MYH09;

InChIKey : WDPFJWLDPVQCAJ-UHFFFAOYSA-N;

Details

Origin ID

C529040;

UMLS CUI

C2348075;

Currated CISMeF NLP mapping
- Darapladib [NCIt concept]
MeSH term(s) associated for indexing
- benzaldehydes [MeSH Descriptor]
- biphenyl compounds [MeSH Descriptor]
- diethylamines [MeSH Descriptor]
- oximes [MeSH Descriptor]
- pyrimidinones [MeSH Descriptor]
- sulfides [MeSH Descriptor]
Pharmacological action(s)
- phospholipase A2 inhibitors [MeSH Descriptor]
Record concept(s)
- SB-480848 [MeSH concept]
- darapladib [MeSH concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Darapladib [NCIt concept]

Keyword's position in hierarchy(ies) :

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