EC131 conjugate

Preferred Label : EC131 conjugate;

MeSH note : folate receptor-targeted drug conjugate prepared by covalently attaching the vitamin folic acid to a potent microtubule-inhibiting agent, maytansinoid DM1, via an intramolecular disulfide bond; has folate receptor-specific antitumor activity; structure in first source;

CISMeF synonym : folate-maytansinoid conjugate;

Is substance : O;

Details

Origin ID

C521363;

UMLS CUI

C1958669;

MeSH term(s) associated for indexing
- folic acid [MeSH Descriptor]
- maytansine [MeSH Descriptor]
Record concept(s)
- EC131 conjugate [MeSH concept]
- folate-maytansinoid conjugate [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Vitamin [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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