platensimycin - CISMeF

Preferred Label : platensimycin;

MeSH note : a pentacyclic ketolide (structurally similar to adamantane) connected by an amide bond to 3-amino-2,4-dihydroxybenzoic acid; inhibits cellular lipid biosynthesis; discovered while screening compounds from Streptomyces platensis bacteria in a South African soil sample with S. aureus bacteria deficient in FabF protein; structure in first source;

MeSH CAS label : benzoic acid, 3-((3-((1S,3S,4S,5aS,9S,9aR)-1,4,5,8,9,9a-hexahydro-3,9-dimethyl-8-oxo-3H-1,4:3,5a-dimethano-2-benzoxepin-9-yl)-1-oxopropyl)amino)-2,4-dihydroxy-;

Is substance : O;

UNII : Q3DQ78KOFY;

Details

Origin ID

C510909;

UMLS CUI

C1722387;

MeSH indexing information
- 3-oxoacyl-(acyl-carrier-protein) synthase [MeSH Descriptor]
- anti-infective agents [MeSH Descriptor]
MeSH term(s) associated for indexing
- adamantane [MeSH Descriptor]
- aminobenzoates [MeSH Descriptor]
- anilides [MeSH Descriptor]
Pharmacological action(s)
- anti-infective agents [MeSH Descriptor]
- fatty acid synthesis inhibitors [MeSH Descriptor]
Record concept(s)
- platensimycin [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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