CTX-M-27, E coli

Preferred Label : CTX-M-27, E coli;

MeSH note : CTX-M-27 showed that residue Gly-240 decreased Km for ceftazidime (205 versus 940 microM), but decreased hydrolytic activity against good substrates, such as cefotaxime (kcat, 113 versus 415 s-1), probably owing to the alteration of beta3 strand positioning during the catalytic process.;

Registry Number MeSH : EC 3.5.2.-;

Is substance : O;

Details

Origin ID

C477098;

UMLS CUI

C1311464;

MeSH term(s) associated for indexing
- beta-Lactamases [MeSH Descriptor]
- escherichia coli proteins [MeSH Descriptor]
Record concept(s)
- CTX-M-27, E coli [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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