N(4)-(2,2-dimethyl-1-methylcarbamoylpropyl)-N(1)-hydroxy-2-hydroxymethyl-3-(4-methoxyphenyl)succinamide

Preferred Label : N(4)-(2,2-dimethyl-1-methylcarbamoylpropyl)-N(1)-hydroxy-2-hydroxymethyl-3-(4-methoxyphenyl)succinamide;

MeSH note : inhibits both TNF-alpha converting enzyme and matrix metalloproteinases; structure in first source;

CISMeF synonym : TNF484; (2S,3R)-N(4)-((S)-2,2-dimethyl-1-methylcarbamoylpropyl)-N(1)-hydroxy-2-hydroxymethyl-3-(4-methoxyphenyl)succinamide; PKF242-484;

MeSH synonym : N(4)-DMHHMPSucc;

Is substance : O;

Details

Origin ID

C455823;

UMLS CUI

C1136508;

MeSH indexing information
- metalloendopeptidases [MeSH Descriptor]
MeSH term(s) associated for indexing
- hydroxamic acids [MeSH Descriptor]
Pharmacological action(s)
- matrix metalloproteinase inhibitors [MeSH Descriptor]
Record concept(s)
- (2S,3R)-N(4)-((S)-2,2-dimethyl-1-methylcarbamoylpropyl)-N(1)-hydroxy-2-hydroxymethyl-3-(4-methoxyphenyl)succinamide [MeSH concept]
- N(4)-(2,2-dimethyl-1-methylcarbamoylpropyl)-N(1)-hydroxy-2-hydroxymethyl-3-(4-methoxyphenyl)succinamide [MeSH concept]
- PKF242-484 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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