doxorubicin-N-(2-hydroxypropyl)methacrylamide galactosamine conjugate

Preferred Label : doxorubicin-N-(2-hydroxypropyl)methacrylamide galactosamine conjugate;

MeSH note : a polymeric anticancer conjugate composed of an N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer backbone and pendant doxorubicin (DOX) linked via a Gly-Phe-Leu-Gly peptide spacer, additionally galactose residues are present to facilitate liver targeting; structure in first source;

MeSH synonym : PK2 antitumor agent;

Is substance : O;

Details

Origin ID

C450921;

UMLS CUI

C1121432;

MeSH term(s) associated for indexing
- doxorubicin [MeSH Descriptor]
- galactosamine [MeSH Descriptor]
- oligopeptides [MeSH Descriptor]
- polymethacrylic acids [MeSH Descriptor]
Record concept(s)
- doxorubicin-N-(2-hydroxypropyl)methacrylamide galactosamine conjugate [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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