Preferred Label : CLEC4M protein, human;
MeSH note : from human; cell-surface receptors that mediate cell-cell interactions within the
immune system by binding to intercellular adhesion molecule-3; DC-SIGN is a C-type
lectin expressed on the surface of dendritic cells (DCs), efficiently binds and transmits
HIVs and simian immunodeficiency viruses to susceptible cells; DC-SIGNR is a closely
related homolog; both can bind to multiple strains of HIV-1, HIV-2, and simian immunodeficiency
virus and transmit these viruses to both T cell lines and human peripheral blood mononuclear
cells; RefSeq NM_014257;
MeSH synonym : DC-SIGN-related protein, human; C-type lectin domain family 4, member M protein, human; DC-SIGNR protein, human; dendritic cell specific intracellular adhesion molecule-3 (ICAM-3) grabbing nonintegrin
related protein, human; L-SIGN protein, human; CD209L protein, human; DC-SIGN2 protein, human; liver-lymph node specific ICAM-3-grabbing nonintegrin, human;
Is substance : O;
Origin ID : C433029;
UMLS CUI : C0966484;
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