pexelizumab - CISMeF

Preferred Label : pexelizumab;

MeSH note : a 25 kDa recombinant, humanized, single-chain antibody that binds to human C5 with a very high affinity & thereby blocks C5 cleavage by C5 convertases; for treatment of patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass;

CISMeF synonym : h5G1.1-scFv;

MeSH hyponym : 5G1.1-SC; H-5G1.1 SCFV;

Is substance : O;

UNII : CHZ6OLQ3UU;

Details

Origin ID

C402724;

UMLS CUI

C0916853;

Currated CISMeF NLP mapping
- Pexelizumab [NCIt concept]
MeSH term(s) associated for indexing
- Single-Chain antibodies [MeSH Descriptor]
- antibodies, monoclonal, humanized [MeSH Descriptor]
Record concept(s)
- h5G1.1-scFv [MeSH concept]
- pexelizumab [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pexelizumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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