2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide

Preferred Label : 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide;

MeSH note : structure in first source; a derivative of A77 1726, the active metabolite of the antirheumatic drug leflunomide, where the isoxazole ring has opened to become a nitrile and an alkyne;

CISMeF synonym : 2-cyano-3-hydroxy-N-(4--(trifluoromethyl)phenyl)-2-hepten-6-ynoic acid; FK778; HMR 1715; MNA 715; MNA-X 920715; X 920715; malononitrilamide 715;

MeSH hyponym : FK-778; FK 778; X-920715; malononitrilamide-715; HMR-1715;

Related MeSH term : MNA-715;

MeSH Related Number : 4B135RK2KL;

Registry Number MeSH : 185915-33-7;

Is substance : O;

Details

Origin ID

C115284;

UMLS CUI

C1622995;

MeSH term(s) associated for indexing
- alkynes [MeSH Descriptor]
- isoxazoles [MeSH Descriptor]
- nitriles [MeSH Descriptor]
Record concept(s)
- 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide [MeSH concept]
- 2-cyano-3-hydroxy-N-(4--(trifluoromethyl)phenyl)-2-hepten-6-ynoic acid [MeSH concept]
- FK778 [MeSH concept]
- HMR 1715 [MeSH concept]
- MNA 715 [MeSH concept]
- MNA-X 920715 [MeSH concept]
- X 920715 [MeSH concept]
- malononitrilamide 715 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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