Y 27632 - CISMeF

Preferred Label : Y 27632;

MeSH note : RN given for di-HCl salt; inhibits Rho-associated protein kinase; inhibits calcium sensitization to affect smooth muscle relaxation; structure in first source;

CISMeF synonym : N-(4-pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide;

MeSH synonym : Y27632; Y-27632;

MeSH Related Number : Y 27632, (4(R)-trans)-isomer; Y 27632, (trans)-isomer; Y 27632, dihydrochloride, (4(R)-trans)-isomer; Y 27632, (4(S)-trans)-isomer; 129758-26-5 ((trans)-isomer); 129830-38-2 ((4(R)-trans)-isomer,di-HCl); 146986-50-7 ((4(R)-trans)-isomer); 146986-51-8 ((4(S)-trans)-isomer);

Registry Number MeSH : 138381-45-0;

Related CAS MeSH : 146986-50-7 (Y 27632, (4(R)-trans)-isomer); 129758-26-5 (Y 27632, (trans)-isomer); 129830-38-2 (Y 27632, dihydrochloride, (4(R)-trans)-isomer); 146986-51-8 (Y 27632, (4(S)-trans)-isomer);

related registry number list (CISMeF) : 129758-26-5 ((trans)-isomer); 129830-38-2 ((4(R)-trans)-isomer,di-HCl); 146986-50-7 ((4(R)-trans)-isomer); 146986-51-8 ((4(S)-trans)-isomer);

Is substance : O;

Details

Origin ID

C108830;

UMLS CUI

C0667301;

MeSH term(s) associated for indexing
- amides [MeSH Descriptor]
- pyridines [MeSH Descriptor]
Pharmacological action(s)
- antihypertensive agents [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
- muscle relaxants, central [MeSH Descriptor]
Record concept(s)
- N-(4-pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide [MeSH concept]
- Y 27632 [MeSH concept]
- Y 27632, (4(R)-trans)-isomer [MeSH concept]
- Y 27632, (4(S)-trans)-isomer [MeSH concept]
- Y 27632, (trans)-isomer [MeSH concept]
- Y 27632, dihydrochloride, (4(R)-trans)-isomer [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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