aloxistatin - CISMeF

Preferred Label : aloxistatin;

MeSH note : a membrane-permeable cysteine protease inhibitor;

CISMeF synonym : E64d inhibitor; EP 453;

MeSH synonym : loxistatin, (2S-(2alpha,3beta(R*)))-isomer; ethyl ( )-(2S,3S)-2,3-epoxy-N-((S)-1-(isopentylcarbamoyl)-3-methylbutyl)succinamate;

MeSH hyponym : ethyl epoxysuccinyl-leucylamido-3-methylbutane; ethyl 3-(3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylate; (2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester; epoxysuccinyl-leucylamide(3-methyl)butane ethyl ester; protease inhibitor E64d; EP-453;

MeSH Related Number : loxistatin; 88321-09-9 (aloxistatin); 96244-68-7;

Registry Number MeSH : 88321-09-9;

Related CAS MeSH : 96244-68-7 (loxistatin);

related registry number list (CISMeF) : 96244-68-7;

Is substance : O;

UNII : L5W337AOUR;

InChIKey : SRVFFFJZQVENJC-IHRRRGAJSA-N;

Details

Origin ID

C108192;

UMLS CUI

C0902566;

Currated CISMeF NLP mapping
- Aloxistatin [NCIt concept]
MeSH term(s) associated for indexing
- leucine [MeSH Descriptor]
Pharmacological action(s)
- cysteine proteinase inhibitors [MeSH Descriptor]
- platelet aggregation inhibitors [MeSH Descriptor]
Record concept(s)
- E64d inhibitor [MeSH concept]
- EP 453 [MeSH concept]
- aloxistatin [MeSH concept]
- loxistatin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Aloxistatin [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients