Preferred Label : negamycin;
MeSH note : broad spectrum hydrazide antibiotic obtained from Streptomyces species; action seems
to be due to its binding to ribosomes & interference with amino coding in protein
synthesis; precursor is probably leucyl-negamycin; minor descriptor (76-85); on-line
& Index Medicus search AMINO ACIDS, DIAMINO (76-85); RN given refers to (threo-L)-isomer;
MeSH synonym : (2-((3R,5R)-3,6-diamino-5-hydroxyhexanoyl)-1-methylhydrazino) acetic acid;
MeSH Related Number : negamycin, (threo-D)-isomer; 38065-91-7 ((threo-D)-isomer); 33404-78-3 (negamycin);
Registry Number MeSH : 33404-78-3;
Related CAS MeSH : 38065-91-7 (negamycin, (threo-D)-isomer);
related registry number list (CISMeF) : 38065-91-7 ((threo-D)-isomer);
Is substance : O;
UNII : B15L87Q2HQ;
Origin ID : C100200;
UMLS CUI : C0068488;
MeSH term(s) associated for indexing
Record concept(s)
Semantic type(s)