semapimod - CISMeF

Preferred Label : semapimod;

MeSH note : macrophage-deactivating agent used to treat experimental autoimmune encephalomyelitis in mice; a tetravalent guanylhydrazone; structure given in first source;

CISMeF synonym : CNI 1493;

MeSH synonym : N,N'-Bis(3,5-bis(1-(carbamimidoylhydrazono)ethyl)phenyl)decanediamide;

MeSH Hyperonym : N,N'-bis(3,5-diacetylphenyl)decanediamide tetrakis(amidinohydrazone) tetrahydrochloride;

MeSH hyponym : CNI-1493; decanediamide, N1,N10-bis(3,5-bis(1-(2-(aminoiminomethyl)hydrazinylidene)ethyl)phenyl)-, methanesulfonate; semapimod tetramesylate; AXD455; decanediamide, N1,N10-bis(3,5-bis(1-(2-(aminoiminomethyl)hydrazinylidene)ethyl)phenyl)-, hydrochloride, hydrate (1:2:4); semapimod HCl; N,N'-bis(3,5-bis(1-((aminoiminomethyl)hydrazono)ethyl)phenyl)decanediamide tetrahydrochloride; semapimod hydrochloride; decanediamide, N1,N10-bis(3,5-bis(1-(2-(aminoiminomethyl)hydrazinylidene)ethyl)phenyl)-, hydrochloride (1:4); CPSI 2364; CPSI-2364 free base; CPSI2364;

MeSH Related Number : 49H2LZA8OM; 8W415THB21; A16WYQ522A;

Is substance : O;

UNII : 9SGW2H1K8P;

InChIKey : PWDYHMBTPGXCSN-VCBMUGGBSA-N;

Details

Origin ID

C097256;

UMLS CUI

C1435441;

Automatic exact mappings (from CISMeF team)
- Semapimod [NCIt concept]
MeSH term(s) associated for indexing
- anilides [MeSH Descriptor]
- guanidines [MeSH Descriptor]
- hydrazones [MeSH Descriptor]
Pharmacological action(s)
- anti-inflammatory agents, non-steroidal [MeSH Descriptor]
- immunosuppressive agents [MeSH Descriptor]
Record concept(s)
- AXD-455 [MeSH concept]
- CNI 1493 [MeSH concept]
- CPSI-2364 [MeSH concept]
- semapimod [MeSH concept]
- semapimod hydrochloride dihydrate [MeSH concept]
- semapimod mesylate [MeSH concept]
- semapimod tetrahydrochloride [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Semapimod [NCIt concept]

Keyword's position in hierarchy(ies) :

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