FTI 277 - CISMeF

Preferred Label : FTI 277;

MeSH note : a ras CAAX (C - Cys; A - aliphatic amino acid; X - Ser or Met) peptidomimetic; inhibits farnesyltransferase; blocks Ras oncogenic signaling by accumulating Ras/Raf complexes in the cytoplasm; structure given in first source;

MeSH synonym : FTI-277;

Is substance : O;

Details

Origin ID

C096856;

UMLS CUI

C0384074;

MeSH term(s) associated for indexing
- methionine [MeSH Descriptor]
Pharmacological action(s)
- enzyme inhibitors [MeSH Descriptor]
- radiation-sensitizing agents [MeSH Descriptor]
Record concept(s)
- FTI 277 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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