Preferred Label : G120R protein, human;
MeSH note : a human growth hormone antagonist; results from the substitution of arginine for glycine
at position 120 in native 22-kDa human growth hormone; shows somatotropin Zn-dependent
agonist and antagonist activity on Nb2 cells; acts as a competitive antagonist to
human growth hormone (GH) due to deficient site binding of the GH receptor;
MeSH synonym : (G120R)hGH protein, human; hGH-G120R protein, human; growth hormone G120R, human;
Is substance : O;
Origin ID : C093172;
UMLS CUI : C1447366;
MeSH term(s) associated for indexing
- Record concept(s)
- Semantic type(s)
